PROGOL applied to discover structural
alerts. Best result (of either human or machine origin) using only the
data given and comparable to the results of methods that use extra information
from biological rodent tests.
PROGOL, used to analyze a class
of calcium-channel activators (molecules), generated a boolean feature
that significantly increases the correlation of two existing features with
the activity variable. The final result is comparable with much more complex
models derived using computational chemistry.
